for premixes and feed additives based on
nanopowders of polyvalent iron oxides
nano Fe+
Nutraceuticals are biologically active feed additives, compositions of biologically active substances intended for direct ingestion or inclusion in food products.
Premix is a technological concept that means premixed homogeneous dry components that are dosed in very small quantities.
The field of application of premixes is compound feed, food, polymer, rubber industry, etc.
nano Fe+ is a colloidal solution of chelated polyvalent nanodispersed iron oxide in pharmacopoeial glycerin.
■■■ Characteristics of nano Fe+.
The chemical formula of polyvalent iron oxide is FeO – Fe2O3 – Fe3O4.
The shape of the particles is spherical.
The size of the particles is from 3 to 50 nm.
The phase state is amorphous, glassy and crystalline.
The color is black.
There is no smell.
- Toxicity.
Indicator of acute toxicity DL50 > 10000 mg/kg; СL50 – not reached.
Skin resorptive effect Not detected.
Irritating action Not detected.
Embryotoxic effect Not detected.
Teratogenic effect Not detected.
Gonadotoxic effect Not detected.
Mutagenic effect Not detected.
Carcinogenic effect Not detected.
Assessment IARC Group 3 (not classified as a human carcinogen). - Ecotoxicity.
Acute toxicity to Daphnia magna Not detected.
Acute fish toxicity CL50 > 1000 mg/l (Leuciscus idus, 48 hours)
Toxic effect on algae Not detected.
Toxic effect on earthworms ESO > 10000 mg/l (Pseudomonas fluorescents).
Mobility and stability Does not form toxic compounds in air and wastewater. Does not transform in the environment.
Bioaccumulation Not a bioaccumulating persistent toxic substance.
- Biotoxicity.
The maximum tolerated dose is 1100 20 450 10 25 3
Semi-lethal dose 2200 60 700 25 45 6
Lethal dose 3200 90 1200 45 60 10 - Technical and environmental characteristics.
Safety According to the degree of impact on the human body, it belongs to the IV safety class. This product is not classified as dangerous according to directives 67/548/EEC and 1999/45/EC. It is not listed in Annexes I of the EU Council Regulation No. 304/2003 “Regarding the export and import of hazardous chemical substances” and in the Priority List of Directive (EEC) No. 793/93 “On the assessment and management of the risks of existing substances”.
Registration number in accordance with Regulation (EC) No. 1907/2006 (REACH)
01-2119457554-33-0023
■■■ Purpose of nano Fe+ additive.
Biologically active feed additive nano Fe+ is a biostimulator of the growth and development of agricultural animals (birds, pigs, large and small cattle, fish), which allows to significantly increase the safety of young animals and the productivity of animals (Table 1).
In parallel with this, the veterinary and sanitary indicators of livestock products are noticeably improving, in particular, the quality of meat, eggs, caviar, etc.